Ab initio Modelling of Proteins for moLEcular replacement

AMPLE is a pipeline for unconventional Molecular Replacement A full description of the pipeline can be found here.

Key Features

• Molecular Replacement using ab initio protein structure predictions
• Molecular Replacement using single/multiple distant homologous structures
• Molecular Replacement using NMR ensembles
• Molecular Replacement using ideal helices
• Molecular Replacement for coiled-coil proteins
• Molecular Replacement using models derived from online databases

Examples of the above can be found here.

Command line options

A list of command line options for AMPLE are available here.